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Recent Sentinel Activity

This recent activity feed provides a list of the last 90 days of Sentinel activity across assessments, publications & presentations, projects, events, etc.

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URL Title Category Date Recent Activity
https://stg.sentinelinitiative.org/methods-data-tools/methods/advancing-scalable-natural-language-processing-approaches-unstructured Advancing Scalable Natural Language Processing Approaches for Unstructured Electronic Health Record Data Methods, Data, & Tools
Advancing Scalable Natural Language Processing Approaches for Unstructured Electronic Health Record Data
Methods, Data, & Tools
https://stg.sentinelinitiative.org/methods-data-tools/methods/making-medicaid-data-more-accessible-through-common-data-models-and-fhir Making Medicaid Data More Accessible Through Common Data Models and FHIR APIs Methods, Data, & Tools
Making Medicaid Data More Accessible Through Common Data Models and FHIR APIs
Methods, Data, & Tools
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/outcome-monitoring-following-erenumab-use-signal Outcome Monitoring Following Erenumab Use: A Signal Identification Analysis Analyses
Outcome Monitoring Following Erenumab Use: A Signal Identification Analysis
Analyses
https://stg.sentinelinitiative.org/methods-data-tools/methods/characterization-covid-19-vaccination-data-sdd-0 Characterization of COVID-19 Vaccination Data in the SDD Methods, Data, & Tools
Characterization of COVID-19 Vaccination Data in the SDD
Methods, Data, & Tools
https://stg.sentinelinitiative.org/methods-data-tools/methods/systematic-process-assessing-fitness-purpose-health-outcomes-computable A Systematic Process for Assessing Fitness-for-Purpose of Health Outcomes for Computable Phenotyping with Electronic Health Records Data Methods, Data, & Tools
A Systematic Process for Assessing Fitness-for-Purpose of Health Outcomes for Computable Phenotyping with Electronic Health Records Data
Methods, Data, & Tools
https://stg.sentinelinitiative.org/news-events/publications-presentations/data-driven-automated-classification-algorithms-acute-0 Data-Driven Automated Classification Algorithms for Acute Health Conditions: Applying PheNorm to COVID-19 Disease Publications and Presentations
Data-Driven Automated Classification Algorithms for Acute Health Conditions: Applying PheNorm to COVID-19 Disease
Publications and Presentations
https://stg.sentinelinitiative.org/methods-data-tools/methods/incorporate-range-frequently-used-engineering-features-ehrs-sentinel Incorporate a Range of Frequently Used Engineering Features from EHRs into the Sentinel Common Data Model in the Sentinel EHR and Claims Linked Data Partner Network Methods, Data, & Tools
Incorporate a Range of Frequently Used Engineering Features from EHRs into the Sentinel Common Data Model in the Sentinel EHR and Claims Linked Data Partner Network
Methods, Data, & Tools
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/hydrochlorothiazide-use-following-labeling-update-include-0 Hydrochlorothiazide Use Following Labeling Update to Include the Risk of Non-Melanoma Skin Cancer: An Interrupted Time Series Analysis Analyses
Hydrochlorothiazide Use Following Labeling Update to Include the Risk of Non-Melanoma Skin Cancer: An Interrupted Time Series Analysis
Analyses
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/intentional-self-harm-following-glucagon-peptide-1-0 Intentional Self-Harm Following Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA) Use in Patients with Obesity: A Descriptive Analysis Analyses
Intentional Self-Harm Following Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA) Use in Patients with Obesity: A Descriptive Analysis
Analyses
https://stg.sentinelinitiative.org/methods-data-tools/methods/evaluate-use-dance-algorithm-find-disconnected-negative-controls-and Evaluate the Use of the DANCE Algorithm to Find Disconnected Negative Controls and Develop a Toolkit Methods, Data, & Tools
Evaluate the Use of the DANCE Algorithm to Find Disconnected Negative Controls and Develop a Toolkit
Methods, Data, & Tools
https://stg.sentinelinitiative.org/methods-data-tools/methods/subset-calibration-methods Subset Calibration Methods Methods, Data, & Tools
Subset Calibration Methods
Methods, Data, & Tools
https://stg.sentinelinitiative.org/methods-data-tools/methods/comparison-signal-detection-and-evaluation-study-designs-inform Comparison of Signal Detection and Evaluation Study Designs to Inform Development of the Pregnancy Safety Framework Methods, Data, & Tools
Comparison of Signal Detection and Evaluation Study Designs to Inform Development of the Pregnancy Safety Framework
Methods, Data, & Tools
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/siponimod-use-among-female-patients-descriptive-analysis Siponimod Use Among Female Patients: A Descriptive Analysis Analyses
Siponimod Use Among Female Patients: A Descriptive Analysis
Analyses
https://stg.sentinelinitiative.org/studies/drugs/biktarvy-bictegraviremtricitabinetenofovir-alafenamide Biktarvy (Bictegravir/Emtricitabine/Tenofovir Alafenamide) & Signal Identification Studies
Biktarvy (Bictegravir/Emtricitabine/Tenofovir Alafenamide) & Signal Identification
Studies
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/characterization-syphilis-testing-and-treatment-infants Characterization of Syphilis Testing and Treatment in Infants in the Mother-Infant Linkage Table in the Sentinel Distributed Database: A Descriptive Analysis Analyses
Characterization of Syphilis Testing and Treatment in Infants in the Mother-Infant Linkage Table in the Sentinel Distributed Database: A Descriptive Analysis
Analyses
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/characterization-syphilis-testing-and-treatment-pregnant Characterization of Syphilis Testing and Treatment in Pregnant Women: A Descriptive Analysis Analyses
Characterization of Syphilis Testing and Treatment in Pregnant Women: A Descriptive Analysis
Analyses
https://stg.sentinelinitiative.org/studies/drugs/mounjaro-tirzepatide Mounjaro (tirzepatide) & Arrhythmia Studies
Mounjaro (tirzepatide) & Arrhythmia
Studies
https://stg.sentinelinitiative.org/methods-data-tools/methods/assessing-performance-major-congenital-malformations-composite-outcome Assessing the Performance of Major Congenital Malformations as a Composite Outcome in Signal Detection and Evaluation Methods, Data, & Tools
Assessing the Performance of Major Congenital Malformations as a Composite Outcome in Signal Detection and Evaluation
Methods, Data, & Tools
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/renal-cell-carcinoma-following-least-180-days-canagliflozin Renal Cell Carcinoma Following At Least 180 Days of Canagliflozin Use in Patients with Type 2 Diabetes Mellitus: A Clone-Censor-Weighted Analysis with Inverse Probability of Treatment Weighting for Active Comparators Analyses
Renal Cell Carcinoma Following At Least 180 Days of Canagliflozin Use in Patients with Type 2 Diabetes Mellitus: A Clone-Censor-Weighted Analysis with Inverse Probability of Treatment Weighting for Active Comparators
Analyses
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/outcome-monitoring-following-prucalopride-and-plecanatide Outcome Monitoring Following Prucalopride and Plecanatide Use: An Active Comparator Signal Identification Analysis with Alternating Exposure-Comparator Roles Analyses
Outcome Monitoring Following Prucalopride and Plecanatide Use: An Active Comparator Signal Identification Analysis with Alternating Exposure-Comparator Roles
Analyses
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/outcome-monitoring-following-ozempic-use-patients-type-2-0 Outcome Monitoring Following Ozempic Use in Patients with Type 2 Diabetes: An Active Comparator Signal Identification Analysis Analyses
Outcome Monitoring Following Ozempic Use in Patients with Type 2 Diabetes: An Active Comparator Signal Identification Analysis
Analyses
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/dihydropyrimidine-dehydrogenase-dpyd-gene-variant-testing Dihydropyrimidine Dehydrogenase (DPYD) Gene Variant Testing Rates and Fluoropyrimidine Use Following Pharmacogenetic Testing Among Incident Fluoropyrimidine Users: A Descriptive Analysis Analyses
Dihydropyrimidine Dehydrogenase (DPYD) Gene Variant Testing Rates and Fluoropyrimidine Use Following Pharmacogenetic Testing Among Incident Fluoropyrimidine Users: A Descriptive Analysis
Analyses
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/outcome-monitoring-following-infliximab-biosimilar-product Outcome Monitoring Following Infliximab Biosimilar Product Use: An Active Comparator Signal Identification Analysis Analyses
Outcome Monitoring Following Infliximab Biosimilar Product Use: An Active Comparator Signal Identification Analysis
Analyses
https://stg.sentinelinitiative.org/news-events/publications-presentations/comparison-manual-and-automated-approaches-developing A Comparison of Manual and Automated Approaches to Developing Computable Algorithms for Identifying Acute Pancreatitis Publications and Presentations
A Comparison of Manual and Automated Approaches to Developing Computable Algorithms for Identifying Acute Pancreatitis
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/prevalence-siponimod-exposure-among-females-childbearing-age Prevalence of Siponimod Exposure Among Females of Childbearing Age in the U.S. Sentinel System Publications and Presentations
Prevalence of Siponimod Exposure Among Females of Childbearing Age in the U.S. Sentinel System
Publications and Presentations
https://stg.sentinelinitiative.org/studies/drugs/ketamine Ketamine & Emergency Department and Pre-Hospital Use Studies
Ketamine & Emergency Department and Pre-Hospital Use
Studies
https://stg.sentinelinitiative.org/studies/drugs/hematopoietic-stem-cell-transplantation-hsct Hematopoietic Stem Cell Transplantation (HSCT) and Thrombotic Microangiopathy (TMA) & Population Characterization Studies
Hematopoietic Stem Cell Transplantation (HSCT) and Thrombotic Microangiopathy (TMA) & Population Characterization
Studies
https://stg.sentinelinitiative.org/news-events/publications-presentations/cautionary-note-plasmode-simulation-studies-setting-causal-0 A Cautionary Note for Plasmode Simulation Studies in the Setting of Causal Inference Publications and Presentations
A Cautionary Note for Plasmode Simulation Studies in the Setting of Causal Inference
Publications and Presentations
https://stg.sentinelinitiative.org/studies/drugs/infliximab-biosimilars Infliximab Biosimilars & Signal Identification Studies
Infliximab Biosimilars & Signal Identification
Studies
https://stg.sentinelinitiative.org/studies/drugs/calcitonin-gene-related-peptide-cgrp-inhibitors Calcitonin Gene-Related Peptide (CGRP) Inhibitors & Gastrointestinal Hypomotility, Constipation or GI dysmotility with Serious Complications and Intentional Self-Harm Studies
Calcitonin Gene-Related Peptide (CGRP) Inhibitors & Gastrointestinal Hypomotility, Constipation or GI dysmotility with Serious Complications and Intentional Self-Harm
Studies
https://stg.sentinelinitiative.org/studies/drugs/mayzent-siponimod Mayzent (Siponimod) & Use in Pregnancy Studies
Mayzent (Siponimod) & Use in Pregnancy
Studies
https://stg.sentinelinitiative.org/news-events/publications-presentations/using-natural-language-processing-clinical-notes-supplement Using Natural Language Processing of Clinical Notes to Supplement Structured Electronic Health Record Data for Phenotyping Smoking and Obesity in a Healthcare System Publications and Presentations
Using Natural Language Processing of Clinical Notes to Supplement Structured Electronic Health Record Data for Phenotyping Smoking and Obesity in a Healthcare System
Publications and Presentations
https://stg.sentinelinitiative.org/studies/drugs/mycophenolate-mofetil-mycophenolic-acid Mycophenolate & Use in Pregnancy Studies
Mycophenolate & Use in Pregnancy
Studies
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/mycophenolate-use-during-pregnancy-descriptive-analysis Mycophenolate Use During Pregnancy: A Descriptive Analysis Analyses
Mycophenolate Use During Pregnancy: A Descriptive Analysis
Analyses
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/frequency-blood-phosphate-monitoring-following-ferric Frequency of Blood Phosphate Monitoring Following Ferric Carboxymaltose (FCM) Administration in Patients in the Sentinel Distributed Database: A Descriptive Analysis Analyses
Frequency of Blood Phosphate Monitoring Following Ferric Carboxymaltose (FCM) Administration in Patients in the Sentinel Distributed Database: A Descriptive Analysis
Analyses
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/utilization-patterns-metformin-patients-polycystic-ovarian Utilization Patterns of Metformin in Patients with Polycystic Ovarian Syndrome: A Descriptive Analysis Analyses
Utilization Patterns of Metformin in Patients with Polycystic Ovarian Syndrome: A Descriptive Analysis
Analyses
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/characterization-metformin-users-polycystic-ovarian-syndrome Characterization of Metformin Users with Polycystic Ovarian Syndrome: A Descriptive Analysis Analyses
Characterization of Metformin Users with Polycystic Ovarian Syndrome: A Descriptive Analysis
Analyses
https://stg.sentinelinitiative.org/methods-data-tools/health-outcomes-interest/cardiac-malformations-algorithm-defined-cardiac Cardiac Malformations Algorithm Defined in "Cardiac Malformations and Oral Clefts Following in Utero Exposure to Cyclobenzaprine: A Propensity Score Stratified Analysis" Methods, Data, & Tools
Cardiac Malformations Algorithm Defined in "Cardiac Malformations and Oral Clefts Following in Utero Exposure to Cyclobenzaprine: A Propensity Score Stratified Analysis"
Methods, Data, & Tools
https://stg.sentinelinitiative.org/methods-data-tools/health-outcomes-interest/oral-clefts-algorithm-defined-cardiac-malformations-and Oral Clefts Algorithm Defined in "Cardiac Malformations and Oral Clefts Following in Utero Exposure to Cyclobenzaprine: A Propensity Score Stratified Analysis" Methods, Data, & Tools
Oral Clefts Algorithm Defined in "Cardiac Malformations and Oral Clefts Following in Utero Exposure to Cyclobenzaprine: A Propensity Score Stratified Analysis"
Methods, Data, & Tools
https://stg.sentinelinitiative.org/news-events/meetings-workshops-trainings/2026-ispe-annual-meeting 2026 ISPE Annual Meeting Sentinel Initiative Events
2026 ISPE Annual Meeting
Sentinel Initiative Events
https://stg.sentinelinitiative.org/methods-data-tools/methods/test-assessment Test Assessment Assessments
Test Assessment
Assessments
https://stg.sentinelinitiative.org/news-events/publications-presentations/combining-treatment-propensity-scores-and-clone-censor Combining Treatment Propensity Scores and Clone-Censor-Weighting to Evaluate Treatment Duration in Active Comparator Studies Publications and Presentations
Combining Treatment Propensity Scores and Clone-Censor-Weighting to Evaluate Treatment Duration in Active Comparator Studies
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/evaluating-data-driven-automated-discovery-disconnected Evaluating Data-Driven Automated Discovery of Disconnected Negative Controls Using Plasmode Simulations Publications and Presentations
Evaluating Data-Driven Automated Discovery of Disconnected Negative Controls Using Plasmode Simulations
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/tree-based-safety-signal-identification-infliximab Tree-Based Safety Signal Identification for Infliximab Biosimilar vs Reference Products Publications and Presentations
Tree-Based Safety Signal Identification for Infliximab Biosimilar vs Reference Products
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/prevalence-cutaneous-lupus-erythematosus-us-populations Prevalence of Cutaneous Lupus Erythematosus in U.S. Populations Using the FDA Sentinel Distributed Database Publications and Presentations
Prevalence of Cutaneous Lupus Erythematosus in U.S. Populations Using the FDA Sentinel Distributed Database
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/finding-needles-same-haystack-comparing-designated-medical Finding Needles in the Same Haystack: Comparing Designated Medical Event vs Untargeted Approach in Signal Identification Publications and Presentations
Finding Needles in the Same Haystack: Comparing Designated Medical Event vs Untargeted Approach in Signal Identification
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/descriptive-analysis-weight-loss-medication-use-including A Descriptive Analysis of Weight Loss Medication Use, Including GLP-1 RA Products, and Intentional Self-Harm among Patients with Obesity in FDA's Sentinel Distributed Database Publications and Presentations
A Descriptive Analysis of Weight Loss Medication Use, Including GLP-1 RA Products, and Intentional Self-Harm among Patients with Obesity in FDA's Sentinel Distributed Database
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/risk-intentional-self-harm-after-glp-1-ra-use-among-patients Risk of Intentional Self-Harm After GLP-1 RA Use Among Patients with Type 2 Diabetes in FDA’s Sentinel Distributed Database Publications and Presentations
Risk of Intentional Self-Harm After GLP-1 RA Use Among Patients with Type 2 Diabetes in FDA’s Sentinel Distributed Database
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/fda-safety-communications-labeling-changes/fda-adds-boxed-warning-labeling-ferric FDA Adds Boxed Warning to Labeling for Ferric Carboxymaltose Injection (Injectafer) to Describe Risk of Low Phosphate Levels Regulatory Impact
FDA Adds Boxed Warning to Labeling for Ferric Carboxymaltose Injection (Injectafer) to Describe Risk of Low Phosphate Levels
Regulatory Impact
https://stg.sentinelinitiative.org/news-events/publications-presentations/risk-renal-cell-carcinoma-following-least-180-days-exposure Risk of Renal Cell Carcinoma Following At Least 180 Days of Exposure to Canagliflozin in U.S. Patients with Type 2 Diabetes Mellitus Publications and Presentations
Risk of Renal Cell Carcinoma Following At Least 180 Days of Exposure to Canagliflozin in U.S. Patients with Type 2 Diabetes Mellitus
Publications and Presentations
https://stg.sentinelinitiative.org/studies/drugs/cyclobenzaprine Cyclobenzaprine & Cardiac Malformations and Oral Clefts Studies
Cyclobenzaprine & Cardiac Malformations and Oral Clefts
Studies
https://stg.sentinelinitiative.org/studies/drugs/injectafer-ferric-carboxymaltose-fcm Injectafer (ferric carboxymaltose, FCM) & Serum Phosphate Testing Studies
Injectafer (ferric carboxymaltose, FCM) & Serum Phosphate Testing
Studies
https://stg.sentinelinitiative.org/news-events/publications-presentations/burden-cutaneous-lupus-erythematosus-commercial-vs-publicly Burden of Cutaneous Lupus Erythematosus in Commercial vs. Publicly Insured Patients in the FDA’s Sentinel Distributed Database Publications and Presentations
Burden of Cutaneous Lupus Erythematosus in Commercial vs. Publicly Insured Patients in the FDA’s Sentinel Distributed Database
Publications and Presentations
https://stg.sentinelinitiative.org/studies/drugs/individual-drug-analyses/cardiac-malformations-and-oral-clefts-following-utero Cardiac Malformations and Oral Clefts Following in Utero Exposure to Cyclobenzaprine: A Propensity Score Stratified Analysis Analyses
Cardiac Malformations and Oral Clefts Following in Utero Exposure to Cyclobenzaprine: A Propensity Score Stratified Analysis
Analyses
https://stg.sentinelinitiative.org/news-events/publications-presentations/development-and-evaluation-targeted-outcome-trees-safety Development and Evaluation of Targeted Outcome Trees for Safety Surveillance using Tree-Based Scan Statistics in the Sentinel System Publications and Presentations
Development and Evaluation of Targeted Outcome Trees for Safety Surveillance using Tree-Based Scan Statistics in the Sentinel System
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/dihydropyrimidine-dehydrogenase-gene-testing-and Dihydropyrimidine Dehydrogenase Gene Testing and Fluoropyrimidine Treatment in the United States – a Sentinel Distributed Database Study Publications and Presentations
Dihydropyrimidine Dehydrogenase Gene Testing and Fluoropyrimidine Treatment in the United States – a Sentinel Distributed Database Study
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/mycophenolate-use-during-pregnancy-analysis-sentinel Mycophenolate Use During Pregnancy: An Analysis in the Sentinel Database Publications and Presentations
Mycophenolate Use During Pregnancy: An Analysis in the Sentinel Database
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/assessing-performance-major-congenital-malformations Assessing the Performance of Major Congenital Malformations as a Composite Outcome in Signal Detection and Evaluation Publications and Presentations
Assessing the Performance of Major Congenital Malformations as a Composite Outcome in Signal Detection and Evaluation
Publications and Presentations
https://stg.sentinelinitiative.org/news-events/publications-presentations/prenatal-care-and-congenital-syphilis-united-states Prenatal Care and Congenital Syphilis in the United States: Characterizing Screening and Treatment Publications and Presentations
Prenatal Care and Congenital Syphilis in the United States: Characterizing Screening and Treatment
Publications and Presentations
https://stg.sentinelinitiative.org/studies/drugs/aimovig-erenumab-0 Aimovig (Erenumab) & Signal Identification Studies
Aimovig (Erenumab) & Signal Identification
Studies
https://stg.sentinelinitiative.org/studies/drugs/cutaneous-lupus-erythematosus Cutaneous Lupus Erythematosus & Prevalence Studies
Cutaneous Lupus Erythematosus & Prevalence
Studies
https://stg.sentinelinitiative.org/studies/drugs/fluoropyrimidine Fluoropyrimidines & Dihydropyrimidine Dehydrogenase Testing Studies
Fluoropyrimidines & Dihydropyrimidine Dehydrogenase Testing
Studies
https://stg.sentinelinitiative.org/studies/drugs/glucagon-peptide-1-receptor-agonists Glucagon-Like Peptide-1 Receptor Agonists & Intentional Self-Harm Studies
Glucagon-Like Peptide-1 Receptor Agonists & Intentional Self-Harm
Studies
https://stg.sentinelinitiative.org/studies/drugs/semaglutide-injectables Semaglutide Injectables & Signal Identification Studies
Semaglutide Injectables & Signal Identification
Studies
https://stg.sentinelinitiative.org/studies/drugs/hydrochlorothiazide-1 Hydrochlorothiazide & Utilization Studies
Hydrochlorothiazide & Utilization
Studies
https://stg.sentinelinitiative.org/studies/drugs/trulance-plecanatide Trulance (Plecanatide) & Signal Identification Studies
Trulance (Plecanatide) & Signal Identification
Studies
https://stg.sentinelinitiative.org/studies/drugs/motegrity-prucalopride Motegrity (Prucalopride) & Signal Identification Studies
Motegrity (Prucalopride) & Signal Identification
Studies
https://stg.sentinelinitiative.org/methods-data-tools/methods/computable-phenotyping-and-validation-studies-venous-thromboembolism-and Computable Phenotyping and Validation Studies: Venous Thromboembolism and Encapsulated Bacterial Infection Methods, Data, & Tools
Computable Phenotyping and Validation Studies: Venous Thromboembolism and Encapsulated Bacterial Infection
Methods, Data, & Tools

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